Sandy Chamoun was born in 1987, and works and lives in Beirut, Lebanon. She studied audio-visual arts at the Université Saint-Joseph de Beyrouth and graduated from the Lebanese University with a BA in acting. She is a founding member of The Great Departed band which is a political satire music project founded in 2013. It released its first album La Bombe in 2016 to acclaim across Arab-majority countries.

Parallel to her work with the band, she performs her own concerts researching and singing Arabic folk songs with social and political critiques. She has sung the repertoire of Sheikh Imam and Mona Meraashli at Metro Al Madina and other venues. She participated as an actor/singer in several theatrical productions: Political Circus, Welada88, and Aghani Servicet (Taxi Songs). These shows were featured at Metro Al-Madina and the Beiteddine Festival 2017.

As an actor, she had a lead role in The Beach House by Roy Dib (2016) and participated in Close to Here, a play by Roy Dib (2017) at Sharjah Biennial. She was an actor in the film Congress of Idling Person by Bassem Saad (2020). Currently she is working on her own music project trilogy FATA 17OCT. She was part of a compilation for the Beirut & Beyond Foundation where she released her second solo track «siret el ro3b» in 2021.

She participated in the Itijahat Festival and the Irtijal Festival in September 2021. She has also worked as a sound designer on two short films, There Is a Baba in our House by Leil Zahra Mortada and Congress of Silly Persons by Bassem Saad in 2021. She was a sound designer for the podcast Test Test Test produced by Oppa research architecture.